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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate CAS 128625-52-5

MF: C18H28N6OP · PF6; MW: 520.39 g/mol

Freight: Less than 10KG USD 35/1kg; 10KG-20kg USD 30/1kg; above 20kg USD 20/1kg;
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CAS 128625-52-5 is an organic compound mainly used as a coupling reagent in organic synthesis.


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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate CAS 128625-52-5 Product Information

Product Name: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
CAS NO: 128625-52-5
EINECS: 603-290-2
Molecular Formula: C18H28F6N6OP2
Molecular Weight: 520.39
Melting Point: 154-156 °C (dec.)(lit.)
Density: 1.438 at 20℃
Solubility: methanol: 25 mg/mL, clear
Storage: 2-8°C
Appearance: White fine crystalline powder

CAS 128625-52-5 applications

  1. Peptide Synthesis: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate (PyBOP) is commonly used as a coupling reagent in peptide synthesis. It facilitates the formation of peptide bonds between amino acid residues, improving the efficiency and yield of peptide synthesis reactions.
  2. Organic Synthesis: PyBOP is a versatile reagent in organic synthesis. It can be used as a coupling agent for the formation of amide, ester, or carbamate bonds. It is particularly useful in reactions involving nucleophiles such as amines, alcohols, or carboxylic acids.
  3. Solid-Phase Peptide Synthesis: PyBOP is often employed in solid-phase peptide synthesis (SPPS) as a coupling reagent. It enables the stepwise assembly of peptide chains on a solid support, facilitating the synthesis of peptides with high purity and efficiency.
  4. Drug Discovery and Development: PyBOP is utilized in the pharmaceutical industry for the synthesis of small molecule drug candidates and peptide therapeutics. It enables the efficient synthesis of peptide-based drugs and drug conjugates that can exhibit enhanced pharmacokinetic properties or targeted delivery.
  5. Other Applications: PyBOP may find use in other areas of chemical research and development. It can be employed in the synthesis of bioconjugates, peptide mimetics, or modified nucleosides. Additionally, it can serve as a reagent in the synthesis of specialty chemicals and materials.
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About The Freight There are two ways, self-pickup and logistics delivery, self-pickup is free of charge, and the calculation method of logistics delivery freight is 35 US dollars per kilogram for less than 10KG, 30 US dollars per kilogramfor more than 10KG-20KG,and 20 US dollars per kilogramfor more than 20KG.
Mass Order More than 100 kg, please contact to negotiate price and freight.
Regarding Delivery Delivery will be arranged within 48 hours after receiving the order On weekdays(Monday through Friday from 9 a.m. to 5 p.m.),.
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  • Global Door To Door Shipping: We ship goods via DHL, Fedex, UPS, TNT,China post, NL Post andother couriers, weightfrom 10g to 1000kg or even bulker.
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