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- Sodium cyanoborohydride CAS 25895-60-7
Sodium cyanoborohydride CAS 25895-60-7
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What is Sodium cyanoborohydride CAS 25895-60-7
The chemical formula of sodium cyanoborohydride, usually referred to as sodium cyanoborohydride or CAS 25895-60-7, is NaBH3CN.It is a moderate yet efficient reducing agent that works well for reducing carbonyl compounds to their corresponding alcohols, such as aldehydes and ketones.
Product Parameter
Product Name: | Sodium cyanoborohydride |
CAS NO: | 25895-60-7 |
Molecular Weight: | 62.84 |
Molecular Formula: | NaBH3CN |
Boiling Point: | 307°C |
Melting point: | >242 °C (dec.) (lit.) |
Density: | 1.083 g/mL at 25 °C |
Appearance: | White powder |
Stability: | Avoid contact with oxides, acids, moisture/humidity |
Synonyms
SodiuM cyanohydridoborate; Sodium cyanoborohydride, 1M solution in THF, AcroSeal; (cyano-C)trihydro-,sodium,(T-4)-Borate(1-); SodiuM (T-4)-(Cyano-C)trihydroborate(1-); sodium,(beta-4)-borate(1-(cyano-c)trihydro-; Sodium cyanoborohydride,Sodium cyanotrihydridoborate; Sodium Cyanotrihydridoborate; Sodium cyanotrihydroborate(1-); Borate(1-), (cyano-κC)trihydro-, sodium, (T-4)-; Sodium cyanotrihydroborate; Sodium borocyanohydride; Sodium cyanoboranuide; Borate(1-), cyanotrihydro-, sodium; Borate(1-), (cyano-κC)trihydro-, sodium (1:1), (T-4)-; Borate(1-), (cyano-C)trihydro-, sodium, (T-4)-; Sodium cyanoboronhydride; Sodium cyanoborohydride, 1M solution in THF, AcroSeal§3;
Sodium cyanoborohydride application
The following are some uses for sodium cyanoborohydride:
1. As a moderate reducing agent:
- Carbonyl compounds, such as aldehydes and ketones, are frequently reduced to their corresponding alcohols by sodium cyanoborohydride.
- Reductive amination is a common method of synthesising amines using sodium cyanoborohydride.
Sodium cyanoborohydride has a milder reactivity than other stronger reducing agents like lithium aluminium hydride (LiAlH4) or sodium borohydride (NaBH4).
2. Stabilization of antibodies: In biochemistry and immunology, sodium cyanoborohydride is used to stabilize antibodies by decreasing and obstructing unreacted aldehyde groups on the antibody’s surface. This prevents non-specific binding and increases the antibody’s stability in a range of applications, including immunohistochemistry and immunoassays.
3. By producing hydrogen on-site, it makes hydrogenation reactions easier and eliminates the requirement for high-pressure hydrogen gas.
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