What is CAS 128625-52-5

PyBOP (benzotriazol-1-yl-yloxytripyrrolidinophosphine hexafluorophosphate) is a reagent used in organic chemistry, namely in peptide synthesis. Its CAS number is 128625-52-5. The substance aids in the creation of peptide bonds between amino acids by acting as a coupling agent.

CAS 12-8625-52-5 Important elements:
PyBOP’s molecular structure is as follows: an oxygen atom connects the benzotriazole moiety (benzotriazol-1-yl-yloxy) to the phosphonium nucleus, which is connected by three pyrrolidine rings.
Benefits: PyBOP’s efficiency and capacity to reduce racemization make it a valued tool in the peptide synthesis process. It is a flexible reagent in organic synthesis since it is soluble in typical organic solvents and can be utilised under mild circumstances.
Safety and Handling: PyBOP, like many peptide coupling agents, needs to be handled carefully. To prevent exposure to the reagent and its byproducts, it is recommended to wear the proper personal protective equipment (PPE) and work in a well-ventilated location.

CAS 128625-52-5 Product Information

Synonyms

CAS 128625-52-5 applications

Some applications for CAS 128625-52-5 include:
1. Peptide synthesis: A common coupling reagent in peptide synthesis is CAS 128625-52-5. It increases the yield and efficiency of the peptide synthesis reaction and encourages the creation of peptide bonds between amino acid residues.
2. Organic synthesis: PyBOP is a versatile reagent used in this process. It is a coupling agent that can be used to create carbamate, ester, or amide linkages.
3. Solid Phase Peptide Synthesis: PyBOP is frequently utilised in SPPS (solid phase peptide synthesis) as a coupling reagent. It facilitates the efficient and high-purity synthesis of peptides by allowing the stepwise assembly of peptide chains on a solid substrate.
4. medicinal development and discovery: PyBOP is employed in the pharmaceutical sector to synthesise peptide therapies and small molecule medicinal candidates.

Cocentech is a reliable source of chemical raw materials in China with a robust logistics network and first-rate customer support. Please do not hesitate to contact us if you would like further information about our goods, including the price.