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Sodium cyanoborohydride

Sodium cyanoborohydride CAS 25895-60-7 is a compound commonly used as a mild substitute for sodium borohydride. Similar to sodium borohydride, sodium cyanoborohydride CAS 25895-60-7 is a common reducing agent used in organic synthesis. Sodium cyanoborohydride is more stable than sodium borohydride and can be stored for long periods of time without significant decomposition.

About Organic Intermediates

Organic intermediates are key components that play a role in the synthesis of complex compounds. They play an important role in organic synthesis and are starting materials or precursors for the production of final products.
A variety of organic intermediates (simple starting materials) can be converted into more complex structures through a series of chemical reactions. The resulting structures can then be further manipulated to produce the desired end products.
There is a wide variety of organic intermediates with different structures and properties that can be used to synthesise different compounds. Some commonly used organic intermediates include alcohols, aldehydes, ketones, acids, esters, amines, and halides.
Organic intermediates offer chemists the possibility of synthesising complex molecules. They facilitate the synthesis of new drugs, the development of new materials, and the advancement of the chemical industry.

Safety Manual for the Use of sodium cyanoborohydride

Although sodium cyanoborohydride is generally considered less toxic than other cyanides, it still needs to be handled with care. The following are some safety precautions for the use of sodium cyanoborohydride:
1. PERSONAL PROTECTION: Please take the necessary precautions when handling, including lab gloves, goggles, and lab coat. Avoid direct contact of your skin, eyes and clothing with sodium cyanoborohydride.
2. Operating environment: Please operate in a well-ventilated area.
3. Handling Disposal: Avoid direct contact with sodium cyanoborohydride and use tools or equipment such as spatulas or spoons for transfer.
4. STORAGE: Store sodium cyanoborohydride in a cool, dry place away from moisture, acids and incompatible materials. Ensure that storage containers are sealed and properly labelled.
5. EMERGENCY ACTION: In case of accidental contact or ingestion, seek immediate medical attention.

Uses of sodium cyanoborohydride

Sodium cyanoborohydride is a versatile compound with many uses in organic synthesis, especially as a mild reducing agent.
1. Reduction of carbonyl compounds: Sodium cyanoborohydride is often used as a reducing agent for the selective reduction of carbonyl compounds to their corresponding alcohols. It provides milder reducing conditions than other reducing agents such as sodium borohydride or lithium aluminium hydride.
2. Reductive amination: Sodium cyanoborohydride is commonly used in reductive amination reactions.
3. Metal-catalysed reduction: Sodium cyanoborohydride can be used in combination with a variety of metal catalysts for the selective reduction of metals.
4. Glycosylation: Sodium cyanoborohydride is used in glycosylation reactions to form glycosidic bonds between sugars and other molecules.
5. Peptide and protein chemistry: Sodium cyanoborohydride is used in peptide and protein chemistry for the reduction of disulfide bonds.

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